Danny Cipriani has been binned by England for the autumn internationals - but clubmate Ben Morgan is brought in out of the wilderness.
Gloucester’s high-profile fly-half is the most notable absentee of those fit and available for the 36-man squad.
It was his match-winning assist in England’s last outing which could well have saved Eddie Jones’ job. And he built on that by being named Premiership player of the month for September.
But Cipriani is nowhere to be seen, while Morgan - a stranger to England colours since the 2015 World Cup - is recalled to hell solve the No.8 crisis in the enforced absence of Billy Vunipola, Nathan Hughes and Sam Simmonds.
Jones has hedged his bets on the captaincy by announcing a job share between Owen Farrell and the fit-again Dylan Hartley .
The Australian said: “They have both been excellent captains for England in the past and will provide a powerful leadership base for us on and off the field."
Jones added: “I’m really happy with the squad. We can only control what we can control and injuries have happened.
“It gives an opportunity for some good new players to play some important Tests for England while players who have been in the squad before, will have to take on more responsibility.”
England play South Africa (3 November), New Zealand (10 November), Japan (17 November) and Australia (24 November).
England squad
Forwards: Tom Curry (Sale Sharks), Charlie Ewels (Bath Rugby), Jamie George (Saracens), Dylan Hartley (co-captain, Northampton Saints), Alec Hepburn (Exeter Chiefs), Ted Hill (Worcester Warriors), Maro Itoje (Saracens), George Kruis (Saracens), Courtney Lawes (Northampton Saints), Zach Mercer (Bath Rugby), Ben Moon (Exeter Chiefs), Ben Morgan (Gloucester Rugby), Michael Rhodes (Saracens), Nick Schonert (Worcester Warriors), Brad Shields (Wasps), Kyle Sinckler (Harlequins) Elliott Stooke (Bath Rugby), Sam Underhill (Bath Rugby), Harry Williams (Exeter Chiefs), Mark Wilson (Newcastle Falcons).
Backs: Chris Ashton (Sale Sharks), Mike Brown (Harlequins), Danny Care (Harlequins), Joe Cokanasiga (Bath Rugby), Elliot Daly (Wasps), Nathan Earle (Harlequins), Owen Farrell (co-captain, Saracens), George Ford (Leicester Tigers), Alex Lozowski (Saracens), Jonny May (Leicester Tigers), Jack Nowell (Exeter Chiefs), Henry Slade (Exeter Chiefs), Ben Te'o (Worcester Warriors), Manu Tuilagi (Leicester Tigers), Richard Wigglesworth (Saracens), Ben Youngs (Leicester Tigers).